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Article

Independent regulation of Rap1 and mitogen-activated protein kinase by the alpha chain of Go.

Neuro-Signals - 1 Jan 2000

Bernasconi Francesca, Malgaroli Antonio, Vallar Lucia

Abstract excerpt

Receptors coupled to G(i/o) proteins stimulate the mitogen-activated protein kinase (MAPK) cascade. The intracellular pathways linking the alpha chains of these G proteins to MAPK activation are not completely understood. One of the signaling molecules which has been suggested to act downstream of Galpha(i/o) is the small G protein Rap1. We investigated the role of Rap1 in MAPK stimulation by Galpha(o) in Chinese...

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Source

Identifiers

PMID: 17085945
DOI: 10.1159/000096734

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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