Article
Contribution of receptor/G protein signaling to cell growth and transformation.
Naunyn-Schmiedeberg's archives of pharmacology - 1 Apr 2000
Gudermann T, Grosse R, Schultz G
Abstract excerpt
While the effects of receptor/G protein systems on intermediary metabolism have been intensively studied, it has only recently been appreciated that G protein-coupled receptors and G proteins (heterotrimeric GTP-binding proteins) play important roles in the regulation of cell growth, differentiation and even transformation. Naturally occurring mutations both in G protein-coupled receptors and in G protein...
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