Article
Interleukin-4 receptor polymorphisms in asthma and allergy: relation to different disease phenotypes.
Acta paediatrica (Oslo, Norway : 1992) - 1 Mar 2010
Hesselmar B, Bergin A-M, Park H, Hahn-Zoric M, Eriksson B, Hanson L-A, Padyukov L
Abstract excerpt
AIM: Inheritance and genetic factors are supposed to influence susceptibility to asthma and allergy. We tested if single nucleotide polymorphisms (SNPs) in the IL4R gene were associated with susceptibility to such diseases, or if they were related to the phenotypic presentation of asthma and allergic rhinoconjunctivitis (ARC). METHODS: Three hundred and nine 12- to 13-year-old children were included. Six SNPs in...
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