Article
Significant association between insertion/deletion polymorphism of the angiotensin-convertig enzyme gene and ankylosing spondylitis.
Molecular vision - 1 Jan 2012
Inanır Ahmet, Yigit Serbulent, Tural Sengul, Ozturk Sibel Demir, Akkanet Songul, Habiboğlu Abdulkadir
Abstract excerpt
PURPOSE: Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease that characteristically affects the sacroiliac joints and the spine. Also iritis and uveitis can be serious complications of AS that can damage the eye and impair vision. The exact pathogenesis of AS remains poorly understood but genetic factors play a key role in its development. Human leukocyte antigen B27 (HLA-B27) is the major...
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