Article
Apolipoprotein E polymorphisms status in Iranian patients with multiple sclerosis.
Journal of the neurological sciences - 15 Sept 2012
Rafiei Mahdi, Zarif Yeganeh Marjan, Sheikholeslami Sara, Gozalpour Elnaz, Ghaffarpour Majid, Hedayati Mehdi
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system. Evidences linking apolipoprotein E (APOE) to myelin repair, neuronal plasticity, and cerebral inflammatory processes suggest that it may be relevant in MS. The main goal of this study was to determine whether the APOE genotypes and alleles are associated with MS patients. MATERIALS AND METHODS: In...
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