Association of angiotensin-converting enzyme/DD genotype with sarcoidosis susceptibility in Slovenian patients.

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Article

Association of angiotensin-converting enzyme/DD genotype with sarcoidosis susceptibility in Slovenian patients.

Medical science monitor : international medical journal of experimental and clinical research - 1 Dec 2007

Salobir Barbara, Medica Igor, Tercelj Marjeta, Kastrin Andrej, Sabovic Miso, Peterlin Borut

Abstract excerpt

BACKGROUND: Sarcoidosis is a multisystemic chronic inflammatory disorder of unknown etiology with multifactorial genetic predisposition. An elevated ACE serum level is considered to be the activity marker of the disease. The involvement of the ACE I/D polymorphism in sarcoidosis susceptibility has been investigated in different populations, but results have been inconclusive. The purpose of this study was to...

Topics

Adult
Female
Genetic Predisposition to Disease
Humans
Male
Peptidyl-Dipeptidase A
Polymorphism, Genetic
Sarcoidosis
Slovenia

Source

Open in PubMed

Identifiers

PMID: 18049432

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