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Article

FG-rich repeats of nuclear pore proteins form a three-dimensional meshwork with hydrogel-like properties.

Science (New York, N.Y.) - 3 Nov 2006

Frey Steffen, Richter Ralf P, Görlich Dirk

Abstract excerpt

Nuclear pore complexes permit rapid passage of cargoes bound to nuclear transport receptors, but otherwise suppress nucleocytoplasmic fluxes of inert macromolecules >/=30 kilodaltons. To explain this selectivity, a sieve structure of the permeability barrier has been proposed that is created through reversible cross-linking between Phe and Gly (FG)-rich nucleoporin repeats. According to this model, nuclear...

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Identifiers

PMID: 17082456
DOI: 10.1126/science.1132516

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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