Article
Nuclear mRNA export requires specific FG nucleoporins for translocation through the nuclear pore complex.
The Journal of cell biology - 24 Sept 2007
Terry Laura J, Wente Susan R
Abstract excerpt
Trafficking of nucleic acids and large proteins through nuclear pore complexes (NPCs) requires interactions with NPC proteins that harbor FG (phenylalanine-glycine) repeat domains. Specialized transport receptors that recognize cargo and bind FG domains facilitate these interactions. Whether different transport receptors utilize preferential FG domains in intact NPCs is not fully resolved. In this study, we use a...
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