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Article

Minimal nuclear pore complexes define FG repeat domains essential for transport.

Nature cell biology - 1 Mar 2004

Strawn Lisa A, Shen Tianxiang, Shulga Nataliya, Goldfarb David S, Wente Susan R

Abstract excerpt

Translocation through nuclear pore complexes (NPCs) requires interactions between receptor-cargo complexes and phenylalanine-glycine (FG) repeats in multiple FG domain-containing NPC proteins (FG-Nups). We have systematically deleted the FG domains of 11 Saccharomyces cerevisiae FG-Nups in various combinations. All five asymmetrically localized FG domains deleted together were non-essential. However, specific...

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Identifiers

PMID: 15039779
DOI: 10.1038/ncb1097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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