Article
Skp2 controls adipocyte proliferation during the development of obesity.
The Journal of biological chemistry - 19 Jan 2007
Sakai Tamon, Sakaue Hiroshi, Nakamura Takehiro, Okada Mitsuru, Matsuki Yasushi, Watanabe Eijiro, Hiramatsu Ryuji, Nakayama Keiko, Nakayama Keiichi I, Kasuga Masato
Abstract excerpt
The increase in the mass of adipose tissue during the development of obesity can arise through an increase in cell size, an increase in cell number, or both. Here we show that long term maintenance of C57BL/6 mice on a high fat diet (for approximately 25 weeks) induces an initial increase in adip...
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