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Article

Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders.

Molecular metabolism - 1 Jun 2017

Zhu Xiaoqiang, Xie Simin, Xu Tian, Wu Xiaohui, Han Min

Abstract excerpt

OBJECTIVE: Identification of additional regulatory factors involved in the onset of obesity is important to understand the mechanisms underlying this prevailing disease and its associated metabolic disorders and to develop therapeutic strategies. Through isolation and analysis of a mutant, we aimed to uncover the function of a Ras-GAP gene, Rasal2 (Ras protein activator like 2), in the development of obesity and...

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Identifiers

PMID: 28580280
DOI: 10.1016/j.molmet.2017.03.003
PMCID: PMC5444017

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