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Article

Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice.

PloS one - 6 Aug 2008

Toh Shen Yon, Gong Jingyi, Du Guoli, Li John Zhong, Yang Shuqun, Ye Jing, Yao Huilan, Zhang Yinxin, Xue Bofu, Li Qing, Yang Hongyuan, Wen Zilong, Li Peng

Abstract excerpt

Fsp27, a member of the Cide family proteins, was shown to localize to lipid droplet and promote lipid storage in adipocytes. We aimed to understand the biological role of Fsp27 in regulating adipose tissue differentiation, insulin sensitivity and energy balance. Fsp27(-/-) mice and Fsp27/lep double deficient mice were generated and we examined the adiposity, whole body metabolism, BAT and WAT morphology, insulin...

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Identifiers

PMID: 18682832
DOI: 10.1371/journal.pone.0002890
PMCID: PMC2483355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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