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Article

Ryanodine receptors and ventricular arrhythmias: emerging trends in mutations, mechanisms and therapies.

Journal of molecular and cellular cardiology - 1 Jan 2007

George Christopher H, Jundi Hala, Thomas N Lowri, Fry Debra L, Lai F Anthony

Abstract excerpt

It has been six years since the first reported link between mutations in the cardiac ryanodine receptor Ca(2+) release channel (RyR2) and catecholaminergic polymorphic ventricular tachycardia (CPVT), a malignant stress-induced arrhythmia. In this time, rapid advances have been made in identifying new mutations, and in understanding how these mutations disrupt normal channel function to cause VT that frequently...

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Share to Arrhythmias, Cardiac
Share to Calcium-Calmodulin-Dependent Protein Kinase Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Tachycardia, Ventricular

Source

Identifiers

PMID: 17081562
DOI: 10.1016/j.yjmcc.2006.08.115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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