Article
Putative association of RUNX1 polymorphisms with IgE levels in a Korean population.
Experimental & molecular medicine - 31 Oct 2006
Chae Soo Cheon, Park Byung Lae, Park Choon-Sik, Ryu Ha-Jung, Yang Yun-Sik, Lee Soo Ok, Choi Yoo Hyun, Kim Eun Mi, Uh Soo Taek, Kim Young Hoon, Kim Ka-Kyung, Oh Bermseok, Chung Hun-Taeg, Kimm Kuchan, Shin Hyoung Doo
Abstract excerpt
RUNX1, a member of the runt domain gene family of transcription factors, encodes a heterodimeric transcription factor and regulates the expression of various genes related to hematopoiesis and myeloid differentiation. RUNX1 has been one of the target genes for research into various autoimmune diseases due to its properties as a transcription factor and functional distribution for chromosomal translocation. In an...
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