Article
Association between genetic variations of the transforming growth factor ß receptor type III and asthma in a Korean population.
Experimental & molecular medicine - 30 Jun 2010
Kim Hee-Kyoo, Jang Tae-Won, Jung Mann-Hong, Park Heung-Woo, Lee Jong-Eun, Shin Eun-Soon, Cho Sang-Heon, Min Kyung-Up, Kim You-Young
Abstract excerpt
Transforming growth factor-beta (TGF-ß) and its receptors have been suggested to play key roles in the pathogenesis of asthma. The aim of this study was to evaluate the effects of genetic variations in the TGF-ß receptor type III (TGFBR3) on asthma and on its related phenotypes in the general population. A cohort of 2,118 subjects aged from 10 to 18 years responded to a questionnaire concerning asthma symptoms...
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