Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dose-dependent and isoform-specific modulation of Ca2+ channels by RGK GTPases.

The Journal of general physiology - 1 Nov 2006

Seu Lillian, Pitt Geoffrey S

Abstract excerpt

Although inhibition of voltage-gated calcium channels by RGK GTPases (RGKs) represents an important mode of regulation to control Ca(2+) influx in excitable cells, their exact mechanism of inhibition remains controversial. This has prevented an understanding of how RGK regulation can be significa...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Action Potentials
Share to Calcium Channels, L-Type
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP Phosphohydrolases

Share to Ion Channel Gating

Share to Isoenzymes

Share to Oocytes

Share to Xenopus laevis

Source

Open in PubMed Open full text

Identifiers

PMID: 17074979
DOI: 10.1085/jgp.200609631
PMCID: PMC2151584

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17074979-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dose-dependent and isoform-specific modulation of Ca2+ channels by RGK GTPases.PMID 17074979Read ↗

Molecular mechanisms, and selective pharmacological rescue, of Rem-inhibited CaV1.2 channels in heart.Semantic proximity Read ↗

Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPasesSemantic proximity Read ↗

Ca(2+) elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart.Semantic proximity Read ↗

Direct inhibition of CaV2.3 by Gem is dynamin dependent and does not require a direct alfa/beta interaction.Semantic proximity Read ↗

Regulators of G protein signaling attenuate the G protein-mediated inhibition of N-type Ca channels.Semantic proximity Read ↗

The role of RGS protein in agonist-dependent relaxation of GIRK currents in Xenopus oocytes.Semantic proximity Read ↗

RGS3 mediates a calcium-dependent termination of G protein signaling in sensory neurons.Semantic proximity Read ↗

Functional assessment of three Rem residues identified as critical for interactions with Ca(2+) channel β subunits.Semantic proximity Read ↗

RGK family G-domain:GTP analog complex structures and nucleotide-binding properties.Semantic proximity Read ↗

Activator of G-protein signaling 1 blocks GIRK channel activation by a G-protein-coupled receptor: apparent disruption of receptor signaling complexes.Semantic proximity Read ↗

Ca(2+) channel inactivation heterogeneity reveals physiological unbinding of auxiliary beta subunits.Semantic proximity Read ↗

Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.