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Article

Polymorphisms in folate metabolizing genes and risk for spontaneous preterm and small-for-gestational age birth.

American journal of obstetrics and gynecology - 1 Nov 2006

Engel Stephanie M, Olshan Andrew F, Siega-Riz Anna Maria, Savitz David A, Chanock Stephen J

Abstract excerpt

OBJECTIVE: Variants in the folate metabolism pathway affect the accumulation of homocysteine are modified by nutrient levels and have been linked to adverse birth outcomes. STUDY DESIGN: We examined the relationship among MTHFR(677), MTHFR(1298), MTR(2756), MTRR(66), and SHMT1(1420), dietary folate intake, and preterm and small-for-gestational-age (SGA) birth in a nested case-control study of black and white...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ferredoxin-NADP Reductase

Share to Folic Acid

Share to Glycine Hydroxymethyltransferase

Share to Infant, Small for Gestational Age

Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 17074544
DOI: 10.1016/j.ajog.2006.07.024

Genes

SHMT1
MTHFR
MTRR
MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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