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Folate metabolizing gene polymorphisms and genetic vulnerability to preterm birth in Korean women.

Genes & genomics - 1 Aug 2021

Kwon Bit Na, Lee Noo Ri, Kim Hyung Jun, Kang Yun Dan, Kim Jong Soo, Park Jin Wan, Jin Han Jun

Abstract excerpt

BACKGROUND: The folate metabolism that converts homocysteine to methionine is closely related to the accumulation of homocysteine. Increased homocysteine levels lead to an impaired antithrombotic function of the vascular endothelium and uterine-placental circulation, resulting in abnormal pregnancy outcomes. Previous studies have reported that gene polymorphisms in folate metabolism are associated with the...

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Identifiers

PMID: 34027569
DOI: 10.1007/s13258-021-01082-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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