Article
Extracting viability landscapes from mutagen-response experiments.
Journal of theoretical biology - 7 Mar 2007
Tannenbaum Emmanuel
Abstract excerpt
This paper outlines a novel approach for determining the importance of various genes to the viability of an organism. The basic idea is to treat a population of cells at various concentrations of mutagen, and determine which genes lose functionality due to genetic drift at the various mutagen concentrations. The more strongly a given collection of genes contributes to the fitness of an organism, the higher the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
