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Article

Diversity of microRNAs in human and chimpanzee brain.

Nature genetics - 1 Dec 2006

Berezikov Eugene, Thuemmler Fritz, van Laake Linda W, Kondova Ivanela, Bontrop Ronald, Cuppen Edwin, Plasterk Ronald H A

Abstract excerpt

We used massively parallel sequencing to compare the microRNA (miRNA) content of human and chimpanzee brains, and we identified 447 new miRNA genes. Many of the new miRNAs are not conserved beyond primates, indicating their recent origin, and some miRNAs seem species specific, whereas others are expanded in one species through duplication events. These data suggest that evolution of miRNAs is an ongoing process...

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Identifiers

PMID: 17072315
DOI: 10.1038/ng1914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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