Article
Evolution of microRNA in primates.
PloS one - 1 Jan 2017
McCreight Jey C, Schneider Sean E, Wilburn Damien B, Swanson Willie J
Abstract excerpt
MicroRNA play an important role in post-transcriptional regulation of most transcripts in the human genome, but their evolution across the primate lineage is largely uncharacterized. A particular miRNA can have one to thousands of messenger RNA targets, establishing the potential for a small change in sequence or overall miRNA structure to have profound phenotypic effects. However, the majority of non-human...
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