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Article

Global coevolution of human microRNAs and their target genes.

Molecular biology and evolution - 1 May 2014

Barbash Shahar, Shifman Sagiv, Soreq Hermona

Abstract excerpt

MicroRNAs (miRNAs) have presumably contributed to the emergence of the novel expression patterns, higher brain functions, and skills underlying human evolution. However, it is incompletely understood how new miRNAs have evolved in the human lineage because their initial emergence predictably entailed deleterious consequences due to their powerful multitarget effects. Here, we report genetic variation and...

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PMID: 24600049
DOI: 10.1093/molbev/msu090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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