Article
Sleep, temperature, activity, and prolactin phenotypes of genetically epilepsy-prone rats.
Comparative medicine - 1 Oct 2006
Toth Linda A, Wang Jia, Bosgraaf Christine, Reichensperger Joel, Hughes Larry F, Faingold Carl L
Abstract excerpt
Sleep-wake disturbances are common in epilepsy, yet the potential adverse effect of seizures on sleep is not well characterized. Genetically epilepsy-prone rats (GEPRs) are a well-studied model of genetic susceptibility to audiogenic seizures. To assess their suitability for investigating relationships between seizures and disordered sleep, we characterized the sleep, activity, and tempera ture patterns of 2 GEPR...
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