Article
Penetrance and expressivity of genes involved in the development of epilepsy in the genetically epilepsy-prone rat (GEPR).
Journal of neurogenetics - 1 Jan 2001
Kurtz B S, Lehman J, Garlick P, Amberg J, Mishra P K, Dailey J W, Weber R, Jobe P C
Abstract excerpt
In order to understand the level of complexity of the epileptic phenotype in the two strains of Genetically Epilepsy-Prone Rats (GEPRs), we determined two important measures of genetic complexity, penetrance and expressivity. Penetrance is the percentage of animals of a specific genotype who express the phenotype associated with that underlying genotype. Expressivity refers to the degree that a particular...
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