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Article

Voluntary Control of Epileptiform Spike–Wave Discharges in Awake Rats

18 May 2017

Abstract excerpt

Genetically inherited absence epilepsy in humans is typically characterized by brief (seconds) spontaneous seizures, which involve spike–wave discharges (SWDs) in the EEG and interruption of consciousness and ongoing behavior. Genetic (inbred) models of this disorder in rats have been used to examine mechanisms, comorbidities, and antiabsence drugs. SWDs have also been proposed as models of complex partial...

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PMID: 28522734
DOI: 10.1523/jneurosci.3235-16.2017

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