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Article

Development of single-cycle replicable human immunodeficiency virus 1 mutants

1 Jan 2011

Abstract excerpt

Non-infectious but antigenic human immunodeficiency virus 1 (HIV-1) particles are essential tool for the research on many topics associated with this virus. Here we report the construction of plasmid containing the HIV-1 genome mutated in the pol gene, which was co-transfected with plasmids expressing the pol gene products reverse transcriptase (RT) and integrase (IN), and the glycoprotein G of vesicular...

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PMID: 21434701
DOI: 10.4149/av_2011_01_15

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