Article
Genetic characterization of simian immunodeficiency virus isolated from an African mandrill.
Archives of virology - 1 Jan 1992
Sakai H, Sakuragi J, Sakuragi S, Shibata R, Hayami M, Ishimoto A, Adachi A
Abstract excerpt
We constructed an infectious molecular clone of simian immunodeficiency virus from an African mandrill (SIVMND). Upon transfection, this clone directed the production of progeny virus particles infectious to and cytopathic for CD4+ human leukemia cells. Thirteen frameshift proviral mutants with an alteration in the eight open reading frames of SIVMND were generated by recombinant DNA techniques, and were analyzed...
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