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Article

Cooperation between VEGF and beta3 integrin during cardiac vascular development.

Blood - 1 Mar 2007

Weis Sara M, Lindquist Jeffrey N, Barnes Leo A, Lutu-Fuga Kimberly M, Cui Jianhua, Wood Malcolm R, Cheresh David A

Abstract excerpt

In the developing myocardium, vascular endothelial growth factor (VEGF)-dependent neovascularization occurs by division of existing vessels, a process that persists for several weeks following birth. During this remodeling phase, mRNA expression of beta3 integrin in the heart decreases significantly as vessel maturation progresses. However, in male mice lacking beta3, coronary capillaries fail to mature and...

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Identifiers

PMID: 17062734
DOI: 10.1182/blood-2005-10-038893
PMCID: PMC1801042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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