Article
Vasculogenesis and Angiogenesis in VEGF Receptor-1 Deficient Mice.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Ho Vivienne C, Fong Guo-Hua
Abstract excerpt
Vascular endothelial growth factor receptor-1 (VEGFR-1)/Flt-1 is a transmembrane tyrosine kinase receptor for VEGF-A, VEGF-B, and placental growth factor (PlGF). VEGFR-1 is an enigmatic molecule whose precise role in postnatal angiogenesis remains controversial. Although many postnatal and adult studies have been performed by manipulating VEGFR-1 ligands, including competitive binding by truncated VEGFR-1...
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