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Article

The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2006

Staalesen Vidar, Knappskog Stian, Chrisanthar Ranjan, Nordgard Silje H, Løkkevik Erik, Anker Gun, Ostenstad Bjørn, Lundgren Steinar, Risberg Terje, Mjaaland Ingvil, Gram Inger Torhild, Kristensen Vessela N, Børresen-Dale Anne-Lise, Lillehaug Johan Richard, Lønning Per Eystein

Abstract excerpt

PURPOSE: p21 is a main effector of growth arrest induced by p53. In addition, a second transcript from the same gene (p21B) has been linked to apoptosis. We previously analyzed p21 status in breast cancer and reported two novel polymorphisms of the p21 gene. In the present study, we present a larger study designed to explore a possible association between these novel polymorphisms and breast cancer. EXPERIMENTAL...

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Share to Cyclin-Dependent Kinase Inhibitor p21

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17062672
DOI: 10.1158/1078-0432.CCR-05-2822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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