Article
Wild-type p53 is not a negative regulator of simian virus 40 DNA replication in infected monkey cells.
Journal of virology - 1 Feb 1993
von der Weth A, Deppert W
Abstract excerpt
To analyze the proposed growth-inhibitory function of wild-type p53, we compared simian virus 40 (SV40) DNA replication in primary rhesus monkey kidney (PRK) cells, which express wild-type p53, and in the established rhesus monkey kidney cell line LLC-MK2, which expresses a mutated p53 that does...
Topics
- Animals
- Cells, Cultured
- DNA Replication
- DNA, Viral
- Down-Regulation
- Gene Expression Regulation, Viral
- Genes, Suppressor
- Macaca mulatta
- Phenotype
- Simian virus 40
- Tumor Suppressor Protein p53