Article
Serologic cross-reactivities poorly reflect allelic relationships in the HLA-B12 and HLA-B21 groups. Dominant epitopes of the alpha 2 helix.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1992
Hildebrand W H, Madrigal J A, Belich M P, Zemmour J, Ward F E, Williams R C, Parham P
Abstract excerpt
Previous analysis has emphasized the correlation between primary structures of class I HLA molecules and their patterns of serologic cross-reactivity. Here we describe the structures of two serologic groups of HLA-B alleles for which this is not the case. HLA-B45, an allele associated with black...
Topics
- Alleles
- Amino Acid Sequence
- Cross Reactions
- Epitopes
- HLA-B Antigens
- Humans
- Molecular Sequence Data
- Polymorphism, Genetic
- Protein Structure, Secondary
- Racial Groups
- Sequence Alignment
