Article
Full-length DQ beta cDNA sequences of HLA-DR2/DQw1 subtypes: genetic interactions between two DQ beta loci generate human class II HLA diversity.
Human immunology - 1 Apr 1990
Wu S K, Lu D, Madden M, Liu C P, Miyokawa N, Bach F H, Saunders T L
Abstract excerpt
Two-dimensional gel electrophoresis of DQ molecules from three different Dw subtypes (Dw2, Dw12, and Dw21/FJO) of the HLA-DR2/DQw1 haplotype reveals that one alpha beta heterodimer of DQ molecule is expressed by each subtype and the DQ beta chain is electrophoretically variable among the three DR2/DQw1 subtypes. We have constructed cDNA libraries from the same homozygous typing cells used in the two-dimensional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.