Mapping of distinct serologic and T cell recognition epitopes on an HLA-DR beta-chain.

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Article

Mapping of distinct serologic and T cell recognition epitopes on an HLA-DR beta-chain.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 1990

Gorski J, Radka S F, Masewicz S, Mickelson E M

Abstract excerpt

A new DR beta-chain allele is defined that is identical to the previously described DR6b molecule except for the first hyperpolymorphic region, where the new allele displays the same polymorphisms found on DR8 and DR12 genes. Two distinct epitopes have been mapped on this new allele. The polymorp...

Topics

Alleles
Amino Acid Sequence
Antibodies, Monoclonal
Base Sequence
Epitopes
HLA-DR Antigens
Humans
Isoantibodies
Models, Molecular
Molecular Sequence Data
Oligonucleotides
Polymerase Chain Reaction
Polymorphism, Genetic
Protein Conformation
T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 1697874

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1697874-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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