Expression of the chronic myelogenous leukemia-associated p210bcr/abl oncoprotein in a murine IL-3 dependent myeloid cell line.

Article

Expression of the chronic myelogenous leukemia-associated p210bcr/abl oncoprotein in a murine IL-3 dependent myeloid cell line.

Oncogene - 1 Feb 1991

Laneuville P, Heisterkamp N, Groffen J

Abstract excerpt

We have studied the effect of a replication-defective murine retroviral vector expressing the chronic myelogenous leukemia associated oncoprotein p210bcr/abl in murine IL-3 dependent myeloid 32D C13(G) cells. This cell line can be induced to differentiate along either the granulocytic or monocyti...

Topics

Cell Cycle
Cell Differentiation
Cell Line
Fusion Proteins, bcr-abl
Granulocyte Colony-Stimulating Factor
Humans
Interleukin-3
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Phenotype
Phosphoproteins
Transfection

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