Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Presence of P210bcrabl is associated with decreased expression of a beta chemokine C10 gene in a P210bcrabl-positive myeloid leukemia cell line.

Molecular medicine (Cambridge, Mass.) - 1 Jan 1999

Lane C M, Guo X Y, Macaluso L H, Yung K C, Deisseroth A B

Abstract excerpt

BACKGROUND: Chronic myelogenous leukemia (CML) is thought to start with the acquisition of the t(9;22) chromosomal translocation that codes for the P210bcrabl tyrosine-specific protein kinase. The CML cells exhibit anchorage-independent cell growth and genetic instability. After the initial phase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokines, CC
Share to DNA, Complementary
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Fusion Proteins, bcr-abl

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to RNA, Neoplasm

Share to Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 10072448
PMCID: PMC2230372

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10072448-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Presence of P210bcrabl is associated with decreased expression of a beta chemokine C10 gene in a P210bcrabl-positive myeloid leukemia cell line.PMID 10072448Read ↗

Clonal evolution in a myeloid cell line transformed to interleukin-3 independent growth by retroviral transduction and expression of p210bcr/ablSemantic proximity Read ↗

Expression of the chronic myelogenous leukemia-associated p210bcr/abl oncoprotein in a murine IL-3 dependent myeloid cell line.Semantic proximity Read ↗

Identification of transcriptional targets associated with the expression of p210 Bcr-Abl.Semantic proximity Read ↗

Increase of bcr-abl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progressionSemantic proximity Read ↗

Peptide containing the BCR oligomerization domain (AA 1-160) reverses the transformed phenotype of p210bcr-abl positive 32D myeloid leukemia cells.Semantic proximity Read ↗

Examination of clinically-derived p210 BCR/ABL1 RhoGEF mutations in a murine bone marrow transplantation model of CML.Semantic proximity Read ↗

Localization of BCR-ABL to F-actin regulates cell adhesion but does not attenuate CML developmentSemantic proximity Read ↗

Expression of p210 and p190 BCR‐ABL due to alternative splicing in chronic myelogenous leukaemiaSemantic proximity Read ↗

BCR/ABL P210 and P190 cause distinct leukemia in transgenic miceSemantic proximity Read ↗

Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantationSemantic proximity Read ↗

Inhibition of class II phosphoinositide 3-kinase gamma expression by p185(Bcr-Abl) contributes to impaired chemotaxis and aberrant homing of leukemic cells.Semantic proximity Read ↗

The Dbl homology domain of BCR is not a simple spacer in P210BCR-ABL of the Philadelphia chromosome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.