Article
No association of single nucleotide polymorphisms in the micro-opioid receptor subunit gene with idiopathic generalized epilepsy.
Epilepsia - 1 Oct 2006
Barratt Catherine, Lai Teck, Nashef Lina, Valentin Antonio, Fisniku Leonora, Moran Nicholas, Asherson Philip, Makoff Andrew
Abstract excerpt
We have investigated the reported association (p = 0.019) between the A118G single nucleotide polymorphism (SNP) of the opioid receptor micro subunit gene (OPRM1) and idiopathic absence epilepsy (IAE). Five SNPs, including A118G, were investigated by association studies in a sample of 240 probands with idiopathic generalized epilepsy (IGE), including 110 with IAE, and 257 controls. No significant association was...
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