A study of TNF-alpha-238 and -308 polymorphisms with different outcomes of persistent hepatitis B virus infection in China.

doi:10.3109/00313025.2010.523696

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A study of TNF-alpha-238 and -308 polymorphisms with different outcomes of persistent hepatitis B virus infection in China.

Pathology - 1 Dec 2010

Wang Binbin, Wang Jing, Zheng Yingying, Zhou Sirui, Zheng Jinxin, Wang Fang, Ma Xu, Zeng Zheng

Abstract excerpt

BACKGROUND: Two common functional polymorphisms in the promoter region of TNF-α located at nucleotides -238 (rs361525) and -308 (rs1800629) have been reported to regulate the expression of tumour necrosis factor alpha (TNF-α) and to be associated with hepatitis B virus (HBV) infection related diseases. However, their frequencies and associations with outcomes of HBV infection are not clear. METHODS: We performed...

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PMID: 21080879
DOI: 10.3109/00313025.2010.523696

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