Article
Incorporation of tRNA into normal and mutant HIV-1.
Biochemical and biophysical research communications - 14 Feb 1991
Kleiman L, Caudry S, Boulerice F, Wainberg M A, Parniak M A
Abstract excerpt
During retroviral assembly, tRNAs are incorporated into the virion, one of which serves as a primer for the reverse transcription reaction. Using two dimensional polyacrylamide gel electrophoresis, we have studied the patterns of tRNAs incorporated into HIV-1 (3B) produced either in the lymphoid cell line H-9 or in the monocytic cell line U937. We have also examined viral tRNA patterns incorporated in a...
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