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Article

Selection of retroviral reverse transcription primer is coordinated with tRNA biogenesis.

Journal of virology - 1 Aug 2003

Kelly Nathan J, Palmer Matthew T, Morrow Casey D

Abstract excerpt

Initiation of retrovirus reverse transcription requires the selection of a tRNA primer from the intracellular milieu. To investigate the features of primer selection, a human immunodeficiency virus type 1 (HIV-1) and a murine leukemia virus (MuLV) were created that require yeast tRNA(Phe) to be supplied in trans for infectivity. Wild-type yeast tRNA(Phe) expressed in mammalian cells was transported to the...

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Share to Genetic Complementation Test
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Share to Nucleic Acid Conformation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RNA, Transfer, Phe

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Identifiers

PMID: 12885888
DOI: 10.1128/jvi.77.16.8695-8701.2003
PMCID: PMC167244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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