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Article

Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles

1 Apr 1994

Abstract excerpt

COS-7 cells transfected with human immunodeficiency virus type 1 (HIV-1) proviral DNA produce virus in which three tRNA species are most abundant in the viral tRNA population. These tRNAs have been identified through RNA sequencing techniques as tRNA(3Lys) the primer tRNA in HIV-1, and members of the tRNA(1,2Lys) isoacceptor family. These RNAs represent 60% of the low-molecular-weight RNA isolated from virus...

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PMID: 7511167
DOI: 10.1128/jvi.68.4.2065-2072.1994

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Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particlesPMID 7511167Read ↗

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Correlation between tRNALys3 aminoacylation and its incorporation into HIV-1.Semantic proximity Read ↗

Incorporation of tRNA into normal and mutant HIV-1.Semantic proximity Read ↗

Primer tRNA3Lys on the viral genome exists in unextended and two-base extended forms within mature human immunodeficiency virus type 1Semantic proximity Read ↗

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Cooperative methylation of human tRNA3Lys at positions A58 and U54 drives the early and late steps of HIV-1 replication.Semantic proximity Read ↗

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