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Article

Caspar, a suppressor of antibacterial immunity in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 31 Oct 2006

Kim Myungjin, Lee Jun Hee, Lee Soo Young, Kim Eunhee, Chung Jongkyeong

Abstract excerpt

Drosophila has a primitive yet highly effective innate immune system. Although the infection-dependent activation mechanisms of the Drosophila immune system are well understood, its inhibitory regulation remains elusive. To find novel suppressors of the immune system, we performed a genetic screening for Drosophila mutants with hyperactivated immune responses and isolated a loss-of-function mutant of caspar whose...

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Identifiers

PMID: 17050695
DOI: 10.1073/pnas.0603238103
PMCID: PMC1637587

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