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Article

Functional dissection of an innate immune response by a genome-wide RNAi screen.

PLoS biology - 1 Aug 2004

Foley Edan, O'Farrell Patrick H

Abstract excerpt

The innate immune system is ancient and highly conserved. It is the first line of defense and the only recognizable immune system in the vast majority of metazoans. Signaling events that convert pathogen detection into a defense response are central to innate immunity. Drosophila has emerged as an invaluable model organism for studying this regulation. Activation of the NF-kappaB family member Relish by the...

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Identifiers

PMID: 15221030
DOI: 10.1371/journal.pbio.0020203
PMCID: PMC434151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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