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Drosophila caspases as guardians of host-microbe interactions

9 Jul 2022

Abstract excerpt

An intact cell death machinery is not only crucial for successful embryonic development and tissue homeostasis, but participates also in the defence against pathogens and contributes to a balanced immune response. Centrally involved in the regulation of both cell death and inflammatory immune responses is the evolutionarily conserved family of cysteine proteases named caspases. The Drosophila melanogaster genome...

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PMID: 35810247
DOI: 10.1038/s41418-022-01038-4

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