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Article

Identification and characterization of arginase II as a chondrocyte phenotype-specific gene.

IUBMB life - 1 Oct 2006

Ko Ah-Ra, Huh Yun-Hyun, Lee Hyun-Chae, Song Woo-Keun, Lee Young-Sup, Chun Jang-Soo

Abstract excerpt

We have previously shown that activation of extracellular signal-regulated protein kinase-1 and -2 (ERK1/2) causes chondrocyte dedifferentiation, which contributes to the destruction of arthritic cartilage. In the present study, we identified genes involved in the ERK1/2 regulation of chondrocyte dedifferentiation. Several genes were identified by subtractive hybridization, and, of these, arginase II was selected...

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Identifiers

PMID: 17050377
DOI: 10.1080/15216540600932993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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