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Recent Research on Chondrocyte Dedifferentiation and Insights for Regenerative Medicine

24 Dec 2024

Abstract excerpt

Chondrocytes maintain the balance of the extracellular matrix by synthesizing glycoproteins, collagen, proteoglycans and hyaluronic acid. Chondrocyte dedifferentiation refers to a process in which chondrocytes lose their mature differentiated phenotype and transform into a fibroblast-like morphology with fewer differentiated stages and inferior function under external stimulation. The important mechanism of...

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PMID: 39716991
DOI: 10.1002/bit.28915

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