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Article

Suppression of discoidin domain receptor 1 expression enhances the chondrogenesis of adipose-derived stem cells.

American journal of physiology. Cell physiology - 1 May 2015

Wu Shun-Cheng, Hsiao Hsu-Feng, Ho Mei-Ling, Hung Yung-Li, Chang Je-Ken, Wang Gwo-Jaw, Wang Chau-Zen

Abstract excerpt

Effectively directing the chondrogenesis of adipose-derived stem cells (ADSCs) to engineer articular cartilage represents an important challenge in ADSC-based articular cartilage tissue engineering. The discoidin domain receptor 1 (DDR1) has been shown to affect cartilage homeostasis; however, little is known about the roles of DDR1 in ADSC chondrogenesis. In this study, we used the three-dimensional culture...

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Identifiers

PMID: 25673773
DOI: 10.1152/ajpcell.00398.2014

Genes

DDR1
DDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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