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Article

Assessment of the gene expression profile of differentiated and dedifferentiated human fetal chondrocytes by microarray analysis.

Arthritis and rheumatism - 1 Feb 2002

Stokes David G, Liu Gang, Coimbra Ibsen B, Piera-Velazquez Sonsoles, Crowl Robert M, Jiménez Sergio A

Abstract excerpt

OBJECTIVE: To study the changes in patterns of gene expression exhibited by human chondrocytes as they dedifferentiate into fibroblastic cells in culture in order to better understand the mechanisms that control this process and its relationship to the phenotypic changes that occur in chondrocytes during the development of osteoarthritis (OA). METHODS: Human fetal epiphyseal chondrocytes (HFCs) were cultured...

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PMID: 11840443
DOI: 10.1002/art.10106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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