Article
Influence of CYP3A5 genetic polymorphism on cyclosporine A metabolism and elimination in Chinese renal transplant recipients.
Acta pharmacologica Sinica - 1 Nov 2006
Chu Xiao-man, Hao Hai-ping, Wang Guang-ji, Guo Lian-qing, Min Pei-qing
Abstract excerpt
AIM: To investigate whether the CYP3A5*3 polymorphism would affect cyclosporine A (CsA) metabolism in Chinese renal transplant patients. METHODS: The CYP3A5*3 genotype was determined in Chinese renal transplant recipients using polymerase chain reaction and amplification of specific alleles (PCR-...
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