Article
Polymorphisms in CYP3A5*3 and MDR1, and haplotype modulate response to plasma levels of tacrolimus in Chinese renal transplant patients.
Annals of transplantation - 1 Jan 2000
Wu Ping, Ni Xuefeng, Wang Mingli, Xu Xianlin, Luo Guanghua, Jiang Yan
Abstract excerpt
BACKGROUND: The purpose of this study was to investigate the effects of polymorphisms in CYP3A5*3, CYP3AP1, and MDR1, and of haplotype, on plasma levels of tacrolimus in Chinese patients after renal transplantation, and to assess the relationship between polymorphisms and the variability of conce...
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